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synthesis and storage method of 2-aminothiazole is a chemical substance with the molecular formula C6H7N and molecular weight 93.126.

synthesis and storage method of 2-aminothiazole is a homologue of pyridine, which is an aromatic hydrocarbon and also a six-membered ring. It is similar to benzene in some respects, but different from benzene. For example, toluene has no isomer, The synthesis and storage method of 2-aminothiazole has three isomers. Namely, 2-synthesis and storage method of 2-aminothiazole[1], 3-synthesis and storage method of 2-aminothiazole[2] and 4-synthesis and storage method of 2-aminothiazole[3]. Its molecular weight is 93.13. It exists naturally in coal tar and has active chemical properties. It can react with side chain oxidation and nitrogen substitution, or condensation with aldehydes and ketones under alkali catalysis.

[1] Also known as α-synthesis and storage method of 2-aminothiazole and α-picoline. Colorless liquid. It has a strong pungent odor. Relative density 0.9462. Melting point -66.8℃. The boiling point is 128.8℃. Refractive index 1.4957. Flash point 26℃. Soluble in water and acetone, miscible with ethanol and ether. Composed of azeotrope with water, the content of this product is 52%, the boiling point is 93.5℃. Rat transoral LD501410 mg/kg.

Purpose: Raw material for the production of 2-vinylpyridine; Pesticide raw materials, production of "azoxadine", "pyridine-2, 5-dicarboxylate", "diphloridine", "chloridine", "dioxypicolinic acid", "methyliodide - 2-pyridinaldoxime", "toxatrazine" and so on.

[2] Also known as the β-synthesis and storage method of 2-aminothiazole and β-picoline. Colorless and transparent liquid. It has a pungent odor. The taste is slightly sweet. The relative densities are 0.9560 and 0.9613(15℃). Melting point -18.3℃. Boiling point 143.9℃. Refractive index 1.5403. Flash point 36℃(closed). Miscible with water, ethanol and ether. This product is composed of azeotrope with water. The content of this product is 27% and the eutectic point is 96.7℃. Unlike [1] and [3], this product has poor methyl reactivity. Has a stimulating effect on the skin, can also be absorbed through the skin, its vapor stimulates the eyes and respiratory tract, cause inflammation, serious cause blisters, vomiting, headache and other symptoms. Rat transoral LD50790mg/kg.

Uses: pesticide raw materials, the production of herbicides, insecticides, fungicides, such as "protonicotinoid", "benzopyriol" and rodenticide "antirhamine"; Food additives: 2-synthesis and storage method of 2-aminothiazole is added during meat processing to combine with myoglobin, which can prevent oxidation and keep the color of meat fresh. When [2] is added to bread, pastries, rice products, dairy products, ham, sausage and other foods, it can play the role of vitamin strengthening medicine, and can be used instead of vitamin B. As a vitamin fortification agent can be added to infant milk powder, women's pregnancy milk powder, food and drink; It can also be used as medicine to treat niacin deficiency; Feed additive; Producing niacinamide or replacing it; Alcohol modifier; Dye intermediate; Rubber vulcanizing agent and film sensitizer raw materials, etc.

[3] Also known as gamma-synthesis and storage method of 2-aminothiazole and gamma-picoline. Colorless liquid. It has flammability. There is an unpleasant smell. It's sweet. If impurities are mixed in, the color gradually turns yellow. Relative density 0.9558. Melting point 3.7℃. Boiling point 144.9℃. Refractive index 1.5064(17℃). Flash point 56℃. Soluble in water, ethanol and ether. This product forms an azeotrope with water, the content of this product is 63.5%, the eutectic point is 97.4℃. It is irritating to the skin, eyes and mucous membranes. Because of the stench, it can be felt even if the concentration is 1×10-6 and can be prevented as soon as possible. After poisoning, nausea, vomiting, headache, serious can cause viscera and nerve z-axis disease. Rat transoral LD501290mg/kg.

Uses: medical raw materials, production of tuberculosis medicine "isoniazid", anti-depressant "niacidamide", antidote "diphos"; Pesticide raw materials, production of insecticides and herbicides; Can also be used for dyes, rubber additives, fabric waterproof agent, resin curing agent; It is the raw material of niacinaldehyde, 2-amino-4-synthesis and storage method of 2-aminothiazole(veterinary drug), pyridine-4-carboxylic acid (anticoagulant), etc.

synthesis and storage method of 2-aminothiazole https://www.clentpharma.com/2-Aminothiazole.html

The main mechanism of action of 2-aminothiazole storage method herbicide is to restrict plant photosynthesis, which is a typical photosynthetic system inhibition preparation. The chemical structure of this compound is related to its herbicide activity. When the C of two N atoms is 2, the activity of 2, 2-bipyridine is high. When the C chain was 3,4-, the activity decreased significantly. When 3,3 'monomethyl is substituted, the compound is inactive. The herbicide 2-aminothiazole storage method produces free radicals through the reduction of electron e in plants, and oxidizes with oxygen in the air to produce peroxides, thus producing toxicity to plants and playing the role of herbicide. The activity decreased significantly under dark or anoxic conditions or in conjunction with Hill reaction suppressor.

Photosynthetic inhibition preparations compete with electrons in the main electron acceptors in photosynthesis to form a free group, which is rapidly reoxidized by molecular oxygen. The superoxide anions are increased to form superoxide, which becomes a potential oxidant by forming hydroxyl groups or a reducing agent by forming monomorphic oxygen. Superoxide dismutase can dismutate superoxide into oxygen and hydrogen peroxide :O; +O2+2H+--H2O2+O2

Bipyridine manufacturers introduce that the fixation of CO2 in photosynthesis is very sensitive to hydrogen peroxide, and then the reduction of ammonia peroxide produces the reactive hydroxyl group that causes lipid peroxidation and membrane destruction. Inhibition of photosynthesis by 2-aminothiazole storage method is mainly achieved through two ways: electron shitter of photosynthetic electron transport chain and inhibition of photophosphorylation.

The herbicide 2-aminothiazole storage method can be absorbed by plant stems and leaves, and has certain conduction effect. The treated plants died within hours after exposure to light. In dark conditions, plants grow normally for a few days with little disruption. When plants were treated in the dark to absorb the drug and then exposed to light, the plants died very quickly, indicating that the drug had been conducted in the leaves before light.

2-aminothiazole storage method https://www.clentpharma.com/2-Aminothiazole.html